The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11. [provided by RefSeq, Sep 2010]
Function
sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity
Synonyms
CEBPD; CCAAT/enhancer binding protein (C/EBP), delta; CELF; CRP3; C/EBP-delta; NF-IL6-beta; CCAAT/enhancer-binding protein delta; c/EBP delta; nuclear factor NF-IL6-beta
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