Human CCR2 blocking peptide (DAG-P1451)

Synthetic Human CCR2 blocking peptide for BL Datasheet

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Nature
Synthetic
Tag/Conjugate
Unconjugated
Sequence Similarities
Belongs to the G-protein coupled receptor 1 family.
Cellular Localization
Cell membrane.
Format
Liquid
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
UniProt ID
Antigen Description
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009]
Function
C-C chemokine receptor activity; CCR2 chemokine receptor binding; chemokine receptor activity; protein homodimerization activity;
Synonyms
CCR2; chemokine (C-C motif) receptor 2; CKR2; CCR-2; CCR2A; CCR2B; CD192; CKR2A; CKR2B; CMKBR2; MCP-1-R; CC-CKR-2; C-C chemokine receptor type 2; MCP-1 receptor; monocyte chemotactic protein 1 receptor; monocyte chemoattractant protein 1 receptor;

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