Human MICU1 blocking peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

CBARA1 peptide is a synthetic peptide corresponding to the internal region of CBARA1 (aa113-126).

Purity

> 95 % by SDS-PAGE.

Format

Lyophilized

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

Reconstitution

MICU1 peptide is supplied as 1mg of dried peptide. When the peptide is reconstituted in 1 mL strile water, the concentration will be 1 mg/mL.

Introduction

This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013]

Entrez Gene ID

Synonyms

MICU1; mitochondrial calcium uptake 1; CALC; EFHA3; MPXPS; CBARA1; calcium uptake protein 1, mitochondrial; ara CALC; atopy-related autoantigen CALC; calcium-binding atopy-related autoantigen 1;