Synthetic Human RASA4 blocking peptide for Apuri, BL, ELISA
Blocking/Immunizing peptide for anti-CAPRI/RASA4 antibody
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Shipped at ambient temperature, store at -20°C.
This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
GTPase activator activity; Ras GTPase activator activity; metal ion binding;
RASA4; RAS p21 protein activator 4; ras GTPase-activating protein 4; CAPRI; GAPL; KIAA0538; Ca2+-promoted Ras inactivator; calcium-promoted Ras inactivator; rasGAP-activating-like protein 2; FLJ59070; MGC131890;