Human RASA4 blocking peptide (CDBP0673)

Synthetic Human RASA4 blocking peptide for Apuri, BL, ELISA Datasheet

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Product Overview
Blocking/Immunizing peptide for anti-CAPRI/RASA4 antibody
Target
CAPRI / RASA4
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Size
100 μg
Storage
Shipped at ambient temperature, store at -20°C.
UniProt ID
Antigen Description
This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function
GTPase activator activity; Ras GTPase activator activity; metal ion binding;
Synonyms
RASA4; RAS p21 protein activator 4; ras GTPase-activating protein 4; CAPRI; GAPL; KIAA0538; Ca2+-promoted Ras inactivator; calcium-promoted Ras inactivator; rasGAP-activating-like protein 2; FLJ59070; MGC131890;

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