Human RASA4 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-CAPRI/RASA4 antibody

Target

CAPRI / RASA4

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function

GTPase activator activity; Ras GTPase activator activity; metal ion binding;

Synonyms

RASA4; RAS p21 protein activator 4; ras GTPase-activating protein 4; CAPRI; GAPL; KIAA0538; Ca2+-promoted Ras inactivator; calcium-promoted Ras inactivator; rasGAP-activating-like protein 2; FLJ59070; MGC131890;