Rabbit Anti-Human RASA4 (C-terminal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

A synthesized peptide derived from human RASA4, corresponding to a region within C-terminal amino acids.

Conjugate

Application Notes

IHC 1:50-1:200
WB 1:1000-3000

General Notes

This product (Catalog No. DPABH-03047) is a rabbit-derived polyclonal antibody raised against human RASA4. This antibody exhibits cross-reactivity with RASA4 from mouse. It has been affinity purified by Protein A. This gene encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene.
DPABH-03047 is suitable for use in IHC 1 (50-1:200), WB 1 (1000-3000) applications.
DPABH-03047 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Entrez Gene ID

UniProt ID