Human CABIN1 peptide

Specificity

Widely expressed in different tissues.

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

Contains 6 TPR repeats.

Purity

70 - 90% by HPLC.

Format

Liquid

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Entrez Gene ID

Antigen Description

Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms. [provided by RefSeq, Jan 2011]

Function

protein phosphatase inhibitor activity;

Synonyms

CABIN1; calcineurin binding protein 1; CAIN; PPP3IN; calcineurin-binding protein cabin-1; calcineurin inhibitor; calcineurin binding protein cabin 1;