Human Bcl2 blocking peptide (CDBP0580)

Synthetic Human Bcl2 blocking peptide for BL Datasheet

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Product Overview
Bcl - 2 ( N - term ) peptide ( human )
Target
Bcl2
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Format
Liquid
Concentration
0.2 mg/ml
Size
100 μg
Buffer
PBS with 100ug BSA 0.1% sodium azide
Storage
Keep as concentrated solution, aliquot and store at 4°C.
UniProt ID
Antigen Description
This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends.
Function
BH3 domain binding; channel activity; identical protein binding; protease binding; protein binding; protein heterodimerization activity; protein homodimerization activity; protein phosphatase 2A binding; sequence-specific DNA binding; transcription factor
Synonyms
BCL2; B-cell CLL/lymphoma 2; apoptosis regulator Bcl-2; Bcl 2; PPP1R50; protein phosphatase 1; regulatory subunit 50; protein phosphatase 1, regulatory subunit 50; Bcl-2;

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