Anti-BCL2 monoclonal antibody (DCABH-9482) Knockout Validated

Mouse Anti-Human BCL2 monoclonal antibody for FC, IHC-P, IHC-Fr, IP, WB, ICC/IF

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
211/E6
Species Reactivity
Mouse, Human
Immunogen
Synthetic peptide corresponding to Bcl-2 aa 41-54.Sequence: GAAPAPGIFSSQPG-Cys
Conjugate
Unconjugated

Applications


Application Notes
Flow Cyt: 1/10; WB: 1/500; ICC/IF: 5 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
BCL2; B-cell CLL/lymphoma 2; apoptosis regulator Bcl-2; Bcl 2; PPP1R50; protein phosphatase 1
Entrez Gene ID
UniProt ID

Product Background


Pathway
ATF-2 transcription factor network, organism-specific biosystem; Activation of BAD and translocation to mitochondria, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Soldini, D; Georgis, A; et al. The combined expression of VPREB3 and ID3 represents a new helpful tool for the routine diagnosis of mature aggressive B-cell lymphomas. HEMATOLOGICAL ONCOLOGY 32:120-125(2014).
Liu, Y; Yang, H; et al. AGGF1 protects from myocardial ischemia/reperfusion injury by regulating myocardial apoptosis and angiogenesis. APOPTOSIS 19:1254-1268(2014).

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