Anti-BCL2 monoclonal antibody (DCABH-9125)

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
cdm3/211/E6
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to Human Bcl-2 aa 41-54 (C terminal).Sequence: GAAPAPGIFSSQPGC
Conjugate
Unconjugated

Target


Alternative Names
BCL2; B-cell CLL/lymphoma 2; apoptosis regulator Bcl-2; Bcl 2; PPP1R50; protein phosphatase 1
Entrez Gene ID
UniProt ID

Product Background


Pathway
ATF-2 transcription factor network, organism-specific biosystem; Activation of BAD and translocation to mitochondria, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Kendrick, SL; Redd, L; et al. BCL2 antibodies targeted at different epitopes detect varying levels of protein expression and correlate with frequent gene amplification in diffuse large B-cell lymphoma. HUMAN PATHOLOGY 45:2144-2153(2014).
Friedberg, JW; Unger, JM; et al. R-CHOP with iodine-131 tositumomab consolidation for advanced stage diffuse large B-cell lymphoma (DLBCL): SWOG S0433. BRITISH JOURNAL OF HAEMATOLOGY 166:382-389(2014).

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