Magic™ Anti-BRCA1 monoclonal antibody (DMAB4923MH)

Armenian Hamster anti-Mouse PDCD1 monoclonal antibody for FC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgM
Clone
HLK-3
Species Reactivity
Human
Immunogen
Peptidecorresponding to amino acids 1839-1863 of the C-terminus of BRCA1.
Conjugate
Unconjugated

Target


Alternative Names
BRCA1; breastcancer 1, early onset; IRIS; PSCP; BRCAI; BRCC1
Entrez Gene ID
UniProt ID

Product Background


Pathway
ATF-2 transcriptionfactor network; ATM mediated phosphorylation of repair proteins; AndrogenReceptor Signaling Pathway; BRCA1-associated genome surveillance complex;Coregulation of Androgen receptor activity; Double-Strand Break Repair;Fanconi anemia pathway; Homologous recombination repair ofreplication-independent double-strand breaks

Citations


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References


Ribeiro-Silva, A; Ramalho, LNZ; et al. p63 correlates with both BRCA1 and cytokeratin 5 in invasive breast carcinomas: further evidence for the pathogenesis of the basal phenotype of breast cancer. HISTOPATHOLOGY 47:458-466(2005).
Jensen, RA; Thompson, ME; et al. BRCA1 protein products: Antibody specificity ... functional motifs ... and secreted tumour suppressors - Reply. NATURE GENETICS 13:269-272(1996).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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