Anti-eIF3E polyclonal antibody (DPABH-15702)

Rabbit anti-Human eIF3E (aa 50-150) polyclonal antibody for IHC-P, ICC/IF, WB, IP Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Chicken, Human, Zebrafish
Immunogen
Synthetic peptide conjugated to KLH derived from within residues 50 - 150 of Human eIF3e.
Conjugate
Unconjugated

Applications


Application Notes
IHC-P: 1 μg/ml; ICC/IF: 5 μg/ml; WB: 1 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
EIF3E; eukaryotic translation initiation factor 3, subunit E; EIF3S6, eukaryotic translation initiation factor 3, subunit 6 48kDa; INT6; eukaryotic translation initiation factor 3 subunit E; eIF3 p48
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S; Cap-dependent Translation Initiation; Eukaryotic Translation Initiation; Formation of a pool of free 40S subunits; Formation of the ternary complex, an

Citations


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References


Bandyopadhyay, A; Lakshmanan, V; et al. Moe1 and spInt6, the fission yeast homologues of mammalian translation initiation factor 3 Subunits p66 (eIF3d) and p48 (eIF3e), respectively, are required for stable association of eIF3 Subunits. JOURNAL OF BIOLOGICAL CHEMISTRY 277:2360-2367(2002).
Mocquet, V; Neusiedler, J; et al. The Human T-Lymphotropic Virus Type 1 Tax Protein Inhibits Nonsense-Mediated mRNA Decay by Interacting with INT6/EIF3E and UPF1. JOURNAL OF VIROLOGY 86:7530-7543(2012).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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