Anti-ZYX monoclonal antibody (DCABH-200)

Rabbit anti-Human ZYX monoclonal antibody for WB, IP, IHC-P, FC, ICC/IF Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS5413
Species Reactivity
Mouse, Human
Immunogen
A synthetic peptide corresponding to residues in Human Zyxin.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/10000 - 1/50000; IP: 1/10 - 1/100; IHC-P: 1/250 - 1/500; Flow Cyt: 1/1000 - 1/10000; ICC/IF: 1/100 - 1/250
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
ZYX; zyxin; zyxin-2; ESP-2; HED-2
Entrez Gene ID
UniProt ID

Product Background


Pathway
E-cadherin signaling in keratinocytes, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; Integrin-mediated cell adhesion, organism-specific biosystem; Stabilization and expansion of the E-cadherin adherens junction, organism-specific biosystem;

Citations


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References


REINHARD, M; JOUVENAL, K; et al. IDENTIFICATION, PURIFICATION, AND CHARACTERIZATION OF A ZYXIN-RELATED PROTEIN THAT BINDS THE FOCAL ADHESION AND MICROFILAMENT PROTEIN VASP (VASODILATOR-STIMULATED PHOSPHOPROTEIN). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 92:7956-7960(1995).
Castellano, F; Montcourrier, P; et al. Inducible recruitment of Cdc42 or WASP to a cell-surface receptor triggers actin polymerization and filopodium formation. CURRENT BIOLOGY 9:351-360(1999).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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