Anti-ZYX monoclonal antibody (DCABH-8990)

Mouse anti-Human ZYX monoclonal antibody for WB, ELISA, ICC, ICC/IF

Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
PM412
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide: PPQPREKVSSIDLEIDS conjugated to KLH by an N-terminal Cysteine residue linker, corresponding to amino acids 134-150 of Human Zyxin
Conjugate
Unconjugated

Applications


Application Notes
WB: 1 - 2 μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
ZYX; zyxin; zyxin-2; ESP-2; HED-2
Entrez Gene ID
UniProt ID

Product Background


Pathway
E-cadherin signaling in keratinocytes, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; Integrin-mediated cell adhesion, organism-specific biosystem; Stabilization and expansion of the E-cadherin adherens junction, organism-specific biosystem;

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References


Gorenne, I; Nakamoto, RK; et al. LPP, a LIM protein highly expressed in smooth muscle. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 285:C674-C685(2003).
Castellano, F; Montcourrier, P; et al. Inducible recruitment of Cdc42 or WASP to a cell-surface receptor triggers actin polymerization and filopodium formation. CURRENT BIOLOGY 9:351-360(1999).

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