Anti-VAMP3 monoclonal antibody, clone MAFB4160

Antibody Isotype

IgG2b

Clone

MAFB4160

Species Reactivity

Human

Immunogen

Recombinant human cellubrevin (1-77aa) purified from E. coli.

Conjugate

Alternative Names

VAMP3; vesicle-associated membrane protein 3 (cellubrevin); vesicle-associated membrane protein 3; CEB; VAMP-3; cellubrevin; synaptobrevin-3;

Entrez Gene ID

UniProt ID

Antigen Description

Cellubrevin, also known as VAMP3, is a member of the Vamp/synaptobrevin family. Vamps, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. Cellubrevin is a vesicular soluble N-ethylmaleimide sensitive factor attachment protein receptor (v-SNARE) homologous to the neuronal synaptobrevins 1/2 and is also a substrate of tetanus neurotoxin.

Pathway

Arf6 trafficking events, organism-specific biosystem; Phagosome, organism-specific biosystem; Phagosome, conserved biosystem; SNARE interactions in vesicular transport, organism-specific biosystem; SNARE interactions in vesicular transport, conserved biosystem;