Specifications
Immunogen
15 residue N-terminal synthetic peptide (Human).
Applications
Application Notes
WB: 1/250 - 1/1000.
Target
Alternative Names
VAMP3; vesicle-associated membrane protein 3 (cellubrevin); vesicle-associated membrane protein 3; CEB; CEB; Cellubrevin; Synaptobrevin 3; Synaptobrevin-3; VAMP 3; VAMP-3; VAMP3; VAMP3_HUMAN; Vesicle associated membrane protein 3; Vesicle-associated membr
Product Background
Antigen Description
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation.
Pathway
Arf6 trafficking events, organism-specific biosystem; Phagosome, organism-specific biosystem; Phagosome, conserved biosystem; SNARE interactions in vesicular transport, organism-specific biosystem; SNARE interactions in vesicular transport, conserved biosystem;
Citations
Publication ()
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