Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide, corresponding to residues in Human VAMP1 (UniProt: P23763).
Applications
Application Notes
WB: 1/1000 - 1/10000; IHC-P: 1/100 - 1/250; ICC/IF: 1/100 - 1/250.
Target
Alternative Names
VAMP1; vesicle-associated membrane protein 1 (synaptobrevin 1); SYB1; vesicle-associated membrane protein 1; VAMP 1; synaptobrevin 1; synaptobrevin-1; VAMP-1; DKFZp686H12131;
Product Background
Antigen Description
Involved in the targeting and/or fusion of transport vesicles to their target membrane.
Pathway
BoNT Light Chain Types B, D, and F cleave VAMP/Synaptobrevin, organism-specific biosystem; Botulinum neurotoxicity, organism-specific biosystem; Disease, organism-specific biosystem; Neuronal System, organism-specific biosystem; Proteolytic cleavage of SNARE complex proteins, organism-specific biosystem; SNARE interactions in vesicular transport, organism-specific biosystem; SNARE interactions in vesicular transport, conserved biosystem;
Citations
Publication ()
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