UQCRFS1 (ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1) is a protein-coding gene. Diseases associated with UQCRFS1 include visceral leishmaniasis, and leishmaniasis, and among its related super-pathways are Electron Transport Chain and Metabolic pathways. GO annotations related to this gene include ubiquinol-cytochrome-c reductase activity and protein complex binding. Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. The transit peptide of the Rieske protein seems to form part of the bc1 complex and is considered to be the subunit 11/IX of that complex (By similarity).
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