Anti-ULK2 monoclonal antibody, clone Y2

Antibody Isotype

IgG1

Clone

Y2

Species Reactivity

Human

Immunogen

ULK2 (AAH34988, 743 a.a. ~ 843 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Alternative Names

ULK2; unc-51-like kinase 2 (C. elegans); unc 51 (C. elegans) like kinase 2; serine/threonine-protein kinase ULK2; ATG1B; KIAA0623; Unc51.2;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified.

Pathway

Regulation of autophagy, organism-specific biosystem; Regulation of autophagy, conserved biosystem; mTOR signaling pathway, organism-specific biosystem; mTOR signaling pathway, conserved biosystem;