Anti-ULK2 (aa 743-843) polyclonal antibody

Species Reactivity

Human

Immunogen

ULK2 (AAH34988, 743 a.a. ~ 843 a.a) partial recombinant protein with GST tag. The sequence is FLRTRTTSVGPSNSGGSLCAMSGRVCVGSPPGPGFGSSPPGAEAAPSLRYVPYGASPPSL EGLITFEAPELPEETLMEREHTDTLRHLNVMLMFTECVLDL

Conjugate

Alternative Names

ULK2; unc-51 like autophagy activating kinase 2; ATG1B; Unc51.2; serine/threonine-protein kinase ULK2;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified.

Pathway

Regulation of autophagy; TOR signaling; mTOR signaling pathway;