Rabbit Anti-Human UBQLN1 (C-terminal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Fusion protein corresponding to residues near the C terminal of human ubiquilin 1

Conjugate

Application Notes

WB: 1:200-1:1000
IHC: 1:25-1:100

General Notes

This product (Catalog No. DPABH-23336) is a rabbit-derived IgG polyclonal antibody raised against human UBQLN1. It has been affinity purified by protein A. This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.
DPABH-23336 is suitable for use in Western blot (WB) (1:200–1:1,000), IHC (1:25–1:100) applications.
DPABH-23336 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

DA41; DSK2; UBQN; XDRP1; PLIC-1

Entrez Gene ID

UniProt ID