Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity.
Pathway
Cytokine Signaling in Immune system; IL1-mediated signaling events; Immune System; Interleukin-1 signaling; Signaling by Interleukins; Toll-like receptor signaling pathway;
Citations
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