Specifications
Immunogen
A synthetic peptide of human TYMP is used for rabbit immunization.
Target
Alternative Names
TYMP; thymidine phosphorylase; ECGF1, endothelial cell growth factor 1 (platelet derived) , MNGIE; gliostatin; tdRPase; TP; ECGF; ECGF1; MNGIE; MEDPS1; MTDPS1; PDECGF; hPD-ECGF;
Product Background
Antigen Description
This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Pathway
Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Drug metabolism - other enzymes, organism-specific biosystem; Drug metabolism - other enzymes, conserved biosystem; Fluoropyrimidine Activity, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem;
Citations
Publication ()
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