Specifications
Immunogen
Recombinant protein fragment corresponding to amino acids 311-482 of Human TYMP produced in E.coli (NP_001944).
Applications
Application Notes
WB: 1/2000; IHC-P: 1/150;
Target
Alternative Names
TYMP; thymidine phosphorylase; ECGF1, endothelial cell growth factor 1 (platelet derived) , MNGIE; gliostatin; tdRPase; TP; ECGF; ECGF1; MNGIE; MEDPS1; MTDPS1; PDECGF; hPD-ECGF;
Product Background
Antigen Description
May have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro.Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
Pathway
Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Drug metabolism - other enzymes, organism-specific biosystem; Drug metabolism - other enzymes, conserved biosystem; Fluoropyrimidine Activity, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem;
Citations
Publication ()
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COA
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