Recombinant human TOP1MT protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 253-601 aa of BC052285
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:500-1:2000
General Notes
This product (Catalog No. DPABH-15292) is a rabbit-derived polyclonal antibody raised against human TOP1MT, targeting the amino acid region 253–601 of the protein. It has been affinity purified by Protein A. This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. DPABH-15292 is suitable for use in Western blot (WB) (1:500–1:2,000) application. DPABH-15292 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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