Anti-TNFRSF11B polyclonal antibody [Biotin] (DPABY-424)

Goat Anti-Human TNFRSF11B polyclonal antibody for WB, ICC, IHC, ELISA(Det)

Specifications


Host Species
Goat
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Osteoprotegerin/TNFRSF11B. Glu22-Leu401 Accession Number AAB53709
Conjugate
Biotin

Applications


Application Notes
Western Blot: 0.1 μg/mL; Immunohistochemistry: 5-15 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-4028 - DPABY-424
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
TNFRSF11B; tumor necrosis factor receptor superfamily, member 11b; OPG; TR1; OCIF; tumor necrosis factor receptor superfamily member 11B
Entrez Gene ID
UniProt ID

Product Background


Pathway
Apoptosis Modulation and Signaling; Cytokine-cytokine receptor interaction; Monoamine Transport; Osteoblast Signaling; Osteoclast Signaling; Osteoclast differentiation; RANKL/RANK Signaling Pathway;

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References


Schrader, J; Rennekamp, W; et al. Cytokine-induced osteoprotegerin expression protects pancreatic beta cells through p38 mitogen-activated protein kinase signalling against cell death. DIABETOLOGIA 50:1243-1247(2007).
Jin, XH; Wu, XX; et al. Delineation of apoptotic genes for synergistic apoptosis of lexatumumab and anthracyclines in human renal cell carcinoma cells by polymerase chain reaction array. ANTI-CANCER DRUGS 23:445-454(2012).

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