Anti-TNFRSF11B polyclonal antibody (DPABH-28597)

Goat Anti-Mouse TNFRSF11B (full length) polyclonal antibody for ELISA, WB, Neut Datasheet

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Specifications


Host Species
Goat
Antibody Isotype
IgG
Species Reactivity
Mouse
Immunogen
Recombinant full length protein (Mouse) expressed in mouse NSO cells.
Conjugate
Unconjugated

Applications


Application Notes
ELISA: 0.5 - 1 μg/ml; WB: 1 - 2 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
TNFRSF11B; tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin); Opg; TR1; OCIF; tumor necrosis factor receptor superfamily member 11B
Entrez Gene ID
UniProt ID

Product Background


Pathway
Cytokine-cytokine receptor interaction; Osteoblast; Osteoclast differentiation;

Citations


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References


Schrader, J; Rennekamp, W; et al. Cytokine-induced osteoprotegerin expression protects pancreatic beta cells through p38 mitogen-activated protein kinase signalling against cell death. DIABETOLOGIA 50:1243-1247(2007).
Lai, FPL; Cole-Sinclair, M; et al. Myeloma cells can directly contribute to the pool of RANKL in bone bypassing the classic stromal and osteoblast pathway of osteoclast stimulation. BRITISH JOURNAL OF HAEMATOLOGY 126:192-201(2004).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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