Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Pathway
Immune System; Innate Immune System; MyD88 cascade initiated on plasma membrane; Toll Like Receptor 10 (TLR10) Cascade; Toll Like Receptor 5 (TLR5) Cascade; Toll Receptor Cascades;
Citations
Publication ()
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