Anti-TLR10 polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

a peptide corresponding to 14 amino acids near the middle of human TLR10.

Conjugate

Unconjugated

Alternative Names

TLR10; toll-like receptor 10; CD290

Entrez Gene ID

81793

UniProt ID

A0A024R9W4

Antigen Description

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2010]

Pathway

Immune System; Innate Immune System; MyD88 cascade initiated on plasma membrane; Toll Like Receptor 10 (TLR10) Cascade; Toll Like Receptor 5 (TLR5) Cascade; Toll-Like Receptors Cascades

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More