Anti-TDG polyclonal antibody (DPABH-23357)

Rabbit anti-Human TDG (aa 250-350) polyclonal antibody for WB, IP Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Mouse, Human
Immunogen
Synthetic peptide conjugated to KLH derived from within residues 250 - 350 of Human Thymine DNA glycosylase.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1μg/ml; IP: 5μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
TDG; thymine-DNA glycosylase; hTDG; G/T mismatch-specific thymine DNA glycosylase
Entrez Gene ID
UniProt ID

Product Background


Pathway
Base Excision Repair; Base excision repair; Base-free sugar-phosphate removal via the single-nucleotide replacement pathway; DNA Repair

Citations


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References


Kim, CH; Darwanto, A; et al. Polymerase Incorporation and Miscoding Properties of 5-Chlorouracil. CHEMICAL RESEARCH IN TOXICOLOGY 23:740-748(2010).
Cortellino, S; Xu, J; et al. Active DNA Demethylation by Thymine DNA Glycosylase.. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS 52:S14-S14(2011).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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