Anti-TCP1 monoclonal antibody, clone 02b

Antibody Isotype

IgG2a

Clone

02b

Species Reactivity

Mouse; Rat; Rabbit; Guinea pig; Hamster; Cow; Dog; Human; Pig; S. cerevisiae; C. elegans; Fruit fly; Monkey

Immunogen

Recombinant Mouse TCP1 alpha protein fragment (carboxy terminal region).

Conjugate

Application Notes

WB: 1/1000; Flow Cyt: 1μg/10⁶ cells; IHC-P: 5 μg/ml;

Alternative Names

TCP1; t-complex protein 1; T-complex protein 1 subunit alpha; TCP-1-A; TCP-1-B; CCT-alpha; TCP-1-alpha; t-complex polypeptide 1; tailless complex polypeptide 1A; tailless complex polypeptide 1B; T-complex protein 1 subunit alpha A; T-complex protein 1 sub

Entrez Gene ID

UniProt ID

Antigen Description

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.

Pathway

Association of TriC/CCT with target proteins during biosynthesis, organism-specific biosystem; Chaperonin-mediated protein folding, organism-specific biosystem; Cooperation of Prefoldin and TriC/CCTin actin and tubulin folding, organism-specific biosystem; Folding of actin by CCT/TriC, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Prefoldin mediated transfer of substrateto CCT/TriC, organism-specific biosystem; Protein folding, organism-specific biosystem;