Anti-TCP1 monoclonal antibody, clone FQS5193

Antibody Isotype

IgG

Clone

FQS5193

Species Reactivity

Mouse; Rat; Rabbit; Human

Immunogen

Synthetic peptide corresponding to residues in Human TCP1 alpha.

Conjugate

Application Notes

WB: 1/1000 - 1/10000; IP: 1/10 - 1/100; IHC-P: 1/100 - 1/250; ICC: 1/50 - 1/100;

Alternative Names

TCP1; t-complex 1; T-complex protein 1 subunit alpha; CCT1; Ccta; D6S230E; tailless complex polypeptide 1; T-complex protein 1, alpha subunit; CCTa; CCT-alpha; TCP-1-alpha;

Entrez Gene ID

UniProt ID

Antigen Description

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.

Pathway

Association of TriC/CCT with target proteins during biosynthesis, organism-specific biosystem; Chaperonin-mediated protein folding, organism-specific biosystem; Cooperation of Prefoldin and TriC/CCTin actin and tubulin folding, organism-specific biosystem; Folding of actin by CCT/TriC, organism-specific biosystem; Formation of tubulin folding intermediates by CCT/TriC, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Prefoldin mediated transfer of substrateto CCT/TriC, organism-specific biosystem;