Rabbit Anti-Human TBX18 (a.a. 350-532) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

Recombinant human TBX18 protein; Source: E. coli derived, PET28a; Tag: 6*His; Domain: 350-532 aa of BC157841

Conjugate

Application Notes

WB: 1:500-1:2000
IHC: 1:20-1:200

General Notes

This product (Catalog No. DPABH-04783) is a rabbit-derived polyclonal antibody raised against human TBX18, targeting the amino acid region 350–532 of the protein. This antibody exhibits cross-reactivity with Human TBX18 from mouse and rat. It has been affinity purified by Protein A. The T-box (Tbx) motif is present in a family of genes whose structural features and expression patterns support their involvement in developmental gene regulation. The Tbx gene family are largely conserved throughout metazoan evolution, and these genes code for putative transcription factors that share a uniquely defining DNA-binding domain. Tbx genes are a family of developmental regulators with more than 20 members recently identified in invertebrates and vertebrates. Mutations in Tbx genes are associated with the onset of several human diseases. Our understanding of functional mechanisms of Tbx products has come mainly from the prototypical T/Brachyury, which is a transcription activator. The Tbx genes constitute a family of transcriptional regulatory genes that are implicated in a variety of developmental processes ranging from the formation of germ layers to the organizational patterning of the central nervous system.
DPABH-04783 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:20–1:200) applications.
DPABH-04783 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

T box 18; T box protein 18; TBX18

Entrez Gene ID

UniProt ID