General Notes
This product (Catalog No. DPABH-23413) is a rabbit-derived polyclonal antibody raised against human STXBP1. This antibody exhibits cross-reactivity with Human STXBP1 from mouse and rat. It has been affinity purified by Protein A. STXBP1, also named as UNC18A, N-Sec1 and p67 belongs to the STXBP/unc-18/SEC1 family. STXBP1 may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. It is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. STXBP1 can interact with syntaxins 1, 2, and 3 but not syntaxin 4. It may play a role in determining the specificity of intracellular fusion reactions.
DPABH-23413 is suitable for use in Western blot (WB) (1:2,000–1:10,000), IHC (1:20–1:200), IF/ICC (1:50–1:500) applications.
DPABH-23413 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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