Specifications
Species Reactivity
Mouse; Rat; Chicken; Dog; Human; Xenopus laevis; Amphibian; Xenopus tropicalis
Immunogen
Other Immunogen Type corresponding to Syntrophin. Whole purified syntrophin from Torpedo californica electric organ postsynaptic membrane.
Applications
Application Notes
ICC/IF: 10 μg/ml; IP: 5 μg/ml; WB: 0.2 μg/ml; Flow Cyt: 0.5μg/106 cells.
Target
Alternative Names
SNTA1; syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component); SNT1, syntrophin, alpha 1 (dystrophin associated protein A1, 59kD, acidic component); alpha-1-syntrophin; pro TGF alpha cytoplasmic domain interacting protein 1; TACI
Product Background
Antigen Description
Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. Plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Binds to phosphatidylinositol 4,5-bisphosphate.
Pathway
Signaling mediated by p38-gamma and p38-delta, organism-specific biosystem;
Citations
Publication ()
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COA
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