Specifications
Immunogen
A synthetic peptide of human SLC7A9 is used for rabbit immunization.
Target
Alternative Names
SLC7A9; solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9; BAT1; CSNU3; B(0,+)-type amino acid transporter 1; b(0,+)AT; glycoprotein-associated amino acid transporter b0,+AT1; solute carrier family 7 (cationic amino acid
Product Background
Antigen Description
This gene encodes a protein that belongs to a family of light subunits of amino acid transporters. This protein plays a role in the high-affinity and sodium-independent transport of cystine and neutral and dibasic amino acids, and appears to function in the reabsorption of cystine in the kidney tubule. Mutations in this gene cause non-type I cystinuria, a disease that leads to cystine stones in the urinary system due to impaired transport of cystine and dibasic amino acids. Alternate transcript variants, which encode the same protein, have been found for this gene.
Pathway
Amino acid transport across the plasma membrane; Basigin interactions; Cell surface interactions at the vascular wall; Hemostasis; Protein digestion and absorption; Protein digestion and absorption; SLC-mediated transmembrane transport; Transmembrane transport of small molecules; Transport of inorganic cations/anions and amino acids/oligopeptides;
Citations
Publication ()
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