Mouse myeloma cell line NS0-derived recombinant mouse SLAM/CD150. Thr25-Pro242 Accession Number Q9QUM4
Conjugate
Biotin
Applications
Application Notes
Western Blot: 1 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL We recommend the following for sandwich ELISA (Capture - Detection): DCABY-4164 - DPABY-655
Target
Alternative Names
SLAMF1; signaling lymphocytic activation molecule family member 1; SLAM; CD150; CDw150; signaling lymphocytic activation molecule; IPO-3;
The Signaling Lymphocytic Activation Molecule (SLAM) family of receptor molecules is a subset of the CD2 family of receptors. SLAM proteins function as co-receptors for lymphocyte activation and/or adhesion and mediate tyrosine phosphorylation signals. SLAM receptor expression is mainly restricted to immune cells. SLAM, also known as CD150, is a transmembrane glycoprotein that is upregulated on activated B cells and T cells but downregulated on Th2 polarized cells. SLAM ligation promotes the activation of Th0/Th1 cells, B cells, eosinophils, mast cell, and macrophages. SLAM also functions as a cellular entry receptor for measles virus.
Pathway
Measles;
Citations
Publication ()
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COA
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