Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the Ser-259 inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.
Pathway
EGFR1 Signaling Pathway;
Citations
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