Anti-SAP18 monoclonal antibody

Antibody Isotype

IgG

Clone

FQS23067(C)

Species Reactivity

Mouse, Rat, Human

Immunogen

Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human SAP18 aa 1-100 (Cysteine residue). The exact sequence is proprietary.Database link: O00422

Conjugate

Unconjugated

Application Notes

WB: 1/1000 - 1/10000; ICC/IF: 1/10 - 1/100; IP: 1/10 - 1/100.

Alternative Names

SAP18; Sin3A-associated protein, 18kDa; sin3A associated protein, 18kDa; histone deacetylase complex subunit SAP18; 2HOR0202; MGC27131; SAP18p; sin3-associated polypeptide p18; sin3-associated polypeptide, p18; cell growth inhibiting protein 38; cell grow

Entrez Gene ID

10284

UniProt ID

O00422

Antigen Description

Component of the SIN3-repressing complex. Enhances the ability of SIN3-HDAC1-mediated transcriptional repression. When tethered to the promoter, it can direct the formation of a repressive complex to core histone proteins. Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism.

Pathway

Exon junction complex (EJC), organism-specific biosystem; Hedgehog Signaling Pathway, organism-specific biosystem; Hedgehog signaling events mediated by Gli proteins, organism-specific biosystem; RNA transport, organism-specific biosystem; RNA transport, conserved biosystem; Regulation of Telomerase, organism-specific biosystem; Regulation of nuclear SMAD2/3 signaling, organism-specific biosystem.

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More