Anti-RPS27 (aa 2-14) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide: PLAKDLLHPSPEE, corresponding to N terminal amino acids 2-14 of Human MPS1.

Conjugate

Application Notes

Peptide ELISA: Antibody detection limit dilution 1:64,000. WB: Use at a concentration of 0.05 - 0.2 μg/ml. Detects a band of approximately 12 kDa (predicted molecular weight: 10 kDa).

Alternative Names

RPS27; ribosomal protein S27; S27; MPS1; MPS-1; 40S ribosomal protein S27; metallopanstimulin 1; metallopan-stimulin 1;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes an extracellular protein that plays a crucial role in the cellular organization of the retina. The encoded protein is assembled and secreted from photoreceptors and bipolar cells as a homo-oligomeric protein complex. Mutations in this gene are responsible for X-linked retinoschisis, a common, early-onset macular degeneration in males that results in a splitting of the inner layers of the retina and severe loss in vision.

Pathway

Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S; Cell Cycle; Cytoplasmic Ribosomal Proteins; Eukaryotic Translation Elongation