Fusion protein corresponding to residues near the N terminal of human ribosomal protein S27
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:200-1:1000 IHC: 1:25-1:100
General Notes
This product (Catalog No. DPABH-28906) is a rabbit-derived IgG polyclonal antibody raised against human RPS27. This antibody exhibits cross-reactivity with RPS27 from mouse and rat. It has been affinity purified by protein A. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the S27e family of ribosomal proteins and component of the 40S subunit. The encoded protein contains a C4-type zinc finger domain that can bind to zinc and may bind to nucleic acid. Mutations in this gene have been identified in numerous melanoma patients and in at least one patient with Diamond-Blackfan anemia (DBA). Elevated expression of this gene has been observed in various human cancers. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. DPABH-28906 is suitable for use in Western blot (WB) (1:200–1:1,000), IHC (1:25–1:100) applications. DPABH-28906 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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