Specifications
Species Reactivity
Human; Mouse
Immunogen
Recombinant protein corresponding to human RICTOR.
Applications
Application Notes
ELISA (1:10000); WB (1:500-1:2000); Immunohistochemistry (1:200-1:1000); Immunofluorescence (1:200-1:1000); Flow Cytometry (1:200-1:400) & The optimal working dilution should be determined by the end user.
Target
Alternative Names
RICTOR; RPTOR independent companion of MTOR, complex 2; rapamycin-insensitive companion of mTOR; AVO3; KIAA1999; MGC39830; PIA; pianissimo; rapamycin insensitive companion of mTOR; hAVO3; AVO3 homolog; TORC2-specific protein AVO3; mAVO3; DKFZp686B11164;
Product Background
Antigen Description
RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).
Pathway
Adaptive Immune System, organism-specific biosystem; CD28 co-stimulation, organism-specific biosystem; CD28 dependent PI3K/Akt signaling, organism-specific biosystem; CXCR3-mediated signaling events, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Class I PI3K signaling events mediated by Akt, organism-specific biosystem; Costimulation by the CD28 family, organism-specific biosystem;
Citations
Publication ()
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COA
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