A synthetic peptide of human RGS7 is used for rabbit immunization.
Conjugate
Unconjugated
Target
Alternative Names
RGS7; regulator of G-protein signaling 7; regulator of G protein signalling 7; regulator of G-protein signalling 7; regulator of G-protein signaling RGS7;
Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes. When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cypolasmic shuttling. May also act by controlling the proteolytic stability of R7 proteins, probably by protecting them from degradation.
Pathway
Calcium Regulation in the Cardiac Cell, organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific bios
Citations
Publication ()
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