Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator (MHC2TA). May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. Isoform RFX-B-delta5 is not involved in the positive regulation of MHC class II genes.
Pathway
Antigen processing and presentation; EGFR1 Signaling Pathway; Primary immunodeficiency; Signaling events mediated by HDAC Class II; Tuberculosis;
Citations
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