Specifications
Immunogen
Full length Human recombinant protein (NP_604389) produced in HEK293T cells.
Applications
Application Notes
WB: 1/500; IHC-P: 1/150; Flow Cyt: 1/100; ICC/IF: 1/100;
Target
Alternative Names
RFXANK; regulatory factor X-associated ankyrin-containing protein; DNA-binding protein RFXANK; ANKRA1; ankyrin repeat containing regulatory factor X associated protein; BLS; DNA binding protein RFXANK; F14150_1; MGC138628; regulatory factor X subunit B; R
Product Background
Antigen Description
Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator (MHC2TA). May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. Isoform RFX-B-delta5 is not involved in the positive regulation of MHC class II genes.
Pathway
Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Primary immunodeficiency, organism-specific biosystem; Primary immunodeficiency, conserved biosystem; Signaling events mediated by HDAC Class II, organism-specific biosystem; Tuberculosis, organism-specific biosystem.
Citations
Publication ()
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COA
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