Anti-RASSF5 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human RASSF5 is used for rabbit immunization.

Conjugate

Alternative Names

RASSF5; Ras association (RalGDS/AF-6) domain family member 5; ras association domain-containing protein 5; Maxp1; NORE1; RAPL; new ras effector 1; Rap1-binding protein; novel Ras effector 1; tumor suppressor RASSF3; Ras effector-like protein; Ras associat

Entrez Gene ID

UniProt ID

Antigen Description

This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene.

Pathway

Leukocyte transendothelial migration, organism-specific biosystem; Leukocyte transendothelial migration, conserved biosystem; Non-small cell lung cancer, organism-specific biosystem; Non-small cell lung cancer, conserved biosystem; Pathways in cancer, organism-specific biosystem; TCR signaling in naive CD4+ T cells, organism-specific biosystem; TCR signaling in naive CD8+ T cells, organism-specific biosystem;