Recombinant fragment containing a sequence corresponding to a region within amino acids 1-154 of Human RAP1A (NP_001010935).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/3000.
Target
Alternative Names
RAP1A; RAP1A, member of RAS oncogene family; ras-related protein Rap-1A; KREV 1; SMGP21; C21KG; G-22K; RAS-related protein RAP1A; Ras-related protein Krev-1; GTP-binding protein smg p21A; RAP1; KREV1; KREV-1;
Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner.
Pathway
ARMS-mediated activation; Adaptive Immune System; Chemokine signaling pathway; Class I PI3K signaling events; EPO signaling pathway; Focal Adhesion;
Citations
Publication ()
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