RAD50 (RAD50 homolog (S. cerevisiae)) is a protein-coding gene. Diseases associated with RAD50 include nijmegen breakage syndrome-like disorder, and nijmegen breakage syndrome, and among its related super-pathways are Non-homologous end joining and Fanconi's Anaemia Pathway. GO annotations related to this gene include 3'-5' exonuclease activity and protein binding, bridging.
Pathway
Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks; BRCA1-associated genome surveillance complex (BASC); Cellular responses to stress; DNA Repair
Citations
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