Anti-RAD50 monoclonal antibody (CABT-35932MH)

Mouse anti-Human RAD50 monoclonal antibody for ICC/IF, IHC-P, IP, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
24C4/3D7
Species Reactivity
Mouse, Human
Immunogen
Fusion protein containing the complete coding region (amino acids 1-425) of RAD50 expressed in E.coli.
Conjugate
Unconjugated

Applications


Application Notes
Flow Cyt: 1μg/106 cells; IHC-P: 1/400; ICC/IF: 1/200; WB: 1/1000;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
RAD50; RAD50 homolog (S. cerevisiae); RAD50 (S. cerevisiae) homolog; DNA repair protein RAD50; hRad50; RAD50 2
Entrez Gene ID
UniProt ID

Product Background


Pathway
Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks, organism-specific biosystem; BARD1 signaling events, organism-specific biosystem; BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem; DNA Repair, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem; Homologous Recombination Repair, organism-specific biosystem; Homologous recombination, organism-specific biosystem; Homologous recombination, conserved biosystem; Homo

Citations


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References


Yabuki, M; Fujii, MM; et al. The MRE11-RAD50-NBS1 complex accelerates somatic hypermutation and gene conversion of immunoglobulin variable regions. NATURE IMMUNOLOGY 6:730-736(2005).
Abbink, P; Lemckert, AAC; et al. Comparative seroprevalence and immunogenicity of six rare serotype recombinant adenovirus vaccine vectors from subgroups B and D. JOURNAL OF VIROLOGY 81:4654-4663(2007).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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