General Notes
This product (Catalog No. DPABH-26325) is a rabbit-derived polyclonal antibody raised against human RAB7A, targeting the amino acid region 1–207 of the protein. This antibody exhibits cross-reactivity with Human RAB7A from mouse and rat. It has been affinity purified by Protein A. RAB7A is a protein-coding gene located on the long arm of human chromosome 3 at position 3q21.3 that encodes the Rab7A protein, a small GTPase belonging to the RAS superfamily of proteins, which plays a central role in regulating intracellular vesicle trafficking, particularly the maturation and fusion events in the late endocytic pathway from late endosomes to lysosomes. The Rab7A protein cycles between GTP-bound (active) and GDP-bound (inactive) states to control these processes, interacting with effector proteins to facilitate cargo degradation and organelle positioning within the cell.
DPABH-26325 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-26325 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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