Anti-RAB11FIP2 monoclonal antibody, clone FQS23305

Antibody Isotype

IgG

Clone

FQS23305

Species Reactivity

Human

Immunogen

Recombinant fragment within Human RAB11-FIP2. The exact sequence is proprietary.Database link: Q7L804

Conjugate

Application Notes

WB: 1/1000 - 1/10000; Flow Cyt: 1/10 - 1/100; IP: 1/10 - 1/100.

Alternative Names

RAB11FIP2; RAB11 family interacting protein 2 (class I); rab11 family-interacting protein 2; KIAA0941; nRip11; Rab11 FIP2; RAB11-FIP2 long isoform; Rab11-FIP2;

Entrez Gene ID

UniProt ID

Antigen Description

A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.

Pathway

Aquaporin-mediated transport, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Regulation of Water Balance by Renal Aquaporins, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem;